BEST3 FISH Probe
The BEST3 FISH probe is designed to hybridize to the BEST3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
BEST3-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
BEST3-20-RE | 20 (40 μL) | 200 μL | ||
BEST3-20-GO | 20 (40 μL) | 200 μL | ||
BEST3-20-GR | 20 (40 μL) | 200 μL | ||
BEST3-20-AQ | 20 (40 μL) | 200 μL | ||
BEST3-20-DIG | 20 (40 μL) | 200 μL | ||
BEST3-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008]
Gene Details
Gene Symbol: BEST3
Gene Name: Bestrophin 3
Chromosome: CHR12: 70047388-70093196
Locus: 12q15
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BEST3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BEST3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping