BEST1 FISH Probe
The BEST1 FISH probe is designed to hybridize to the BEST1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BEST1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BEST1-20-RE | 20 (40 μL) | 200 μL |  |
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| BEST1-20-GO | 20 (40 μL) | 200 μL |  |
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| BEST1-20-GR | 20 (40 μL) | 200 μL |  |
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| BEST1-20-AQ | 20 (40 μL) | 200 μL |  |
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| BEST1-20-DIG | 20 (40 μL) | 200 μL |  |
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| BEST1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
Gene Details
Gene Symbol: BEST1
Gene Name: Bestrophin 1
Chromosome: CHR11: 61717355-61731935
Locus: 11q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BEST1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BEST1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping