BCR Break Apart FISH Probe
Empire Genomics’ BCR Break Apart FISH Probe is designed to flank the BCR gene and is typically used for detecting BCR rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BCRBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BCRBA-20-AQOR | 20 (40 μL) | 200 μL |
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| BCRBA-20-GOGR | 20 (40 μL) | 200 μL |
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| BCRBA-20-GORE | 20 (40 μL) | 200 μL |
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| BCRBA-20-GRGO | 20 (40 μL) | 200 μL |
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| BCRBA-20-GROR | 20 (40 μL) | 200 μL |
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| BCRBA-20-GRRE | 20 (40 μL) | 200 μL |
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| BCRBA-20-REGO | 20 (40 μL) | 200 μL |
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| BCRBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: BCR
Gene Name: BCR, RhoGEF And GTPase Activating Protein
Chromosome: CHR22: 23522551-23660224
Locus: 22q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BCR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping