BCLX FISH Probe
The BCLX FISH probe is designed to hybridize to the BCLX gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCL2L1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BCL2L1-20-RE | 20 (40 μL) | 200 μL |  |
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| BCL2L1-20-GO | 20 (40 μL) | 200 μL |  |
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| BCL2L1-20-GR | 20 (40 μL) | 200 μL |  |
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| BCL2L1-20-AQ | 20 (40 μL) | 200 μL |  |
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| BCL2L1-20-DIG | 20 (40 μL) | 200 μL |  |
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| BCL2L1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: BCL2L1
Gene Name: BCL2 Like 1
Chromosome: CHR20: 30252260-30310656
Locus: 20q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BCLX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCL2L1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping