BCLF-1 FISH Probe
The BCLF-1 FISH probe is designed to hybridize to the BCLF-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TSN-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
TSN-20-RE | 20 (40 μL) | 200 μL | ||
TSN-20-GO | 20 (40 μL) | 200 μL | ||
TSN-20-GR | 20 (40 μL) | 200 μL | ||
TSN-20-AQ | 20 (40 μL) | 200 μL | ||
TSN-20-DIG | 20 (40 μL) | 200 μL | ||
TSN-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: TSN
Gene Name: Translin
Chromosome: CHR2: 122513120-122525428
Locus: 2q14.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: BCLF-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TSN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping