BCL6 FISH Probe
The BCL6 FISH probe is designed to hybridize to the BCL6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
BCL6-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
BCL6-20-RE | 20 (40 μL) | 200 μL | ||
BCL6-20-GO | 20 (40 μL) | 200 μL | ||
BCL6-20-GR | 20 (40 μL) | 200 μL | ||
BCL6-20-AQ | 20 (40 μL) | 200 μL | ||
BCL6-20-DIG | 20 (40 μL) | 200 μL | ||
BCL6-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: BCL6
Gene Name: B-cell CLL/lymphoma 6
Chromosome: CHR3: 187439164-187463513
Locus: 3q27.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BCL6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCL6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping