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BCL2L1 FISH Probe

The BCL2L1 FISH probe is designed to hybridize to the BCL2L1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
BCL2L1-20-OR  (Standard Design) 20 (40 μL) 200 μL
BCL2L1-20-RE 20 (40 μL) 200 μL
BCL2L1-20-GO 20 (40 μL) 200 μL
BCL2L1-20-GR 20 (40 μL) 200 μL
BCL2L1-20-AQ 20 (40 μL) 200 μL
BCL2L1-20-DIG 20 (40 μL) 200 μL
BCL2L1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]

Gene Details

Gene Symbol: BCL2L1

Gene Name: BCL2 Like 1

Chromosome: CHR20: 30252260-30310656

Locus: 20q11.21

Gene Diseases

The BCL2L1 gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
49,XXXXX Syndrome
Aagenaes Syndrome
Abderhalden-Kaufmann-Lignac Syndrome
Abrikosov's Tumor
Achard Syndrome
Achard-Thiers Syndrome
Acquired Hypoprothrombinemia
Acrocephalopolydactylous Dysplasia
Acrocephalopolysyndactyly Type II
Acrootoocular Syndrome
Acrorenal Syndrome
Acute Retroviral Syndrome
Adenocarcinoid Tumor
Adenocarcinoma
Adenoma
Akaba Hayasaka Syndrome
Akesson Syndrome
Aloi Tomasini Isaia Syndrome
Alsing Syndrome
Ameloonychohypohidrotic Syndrome
Androblastoma Of Ovary
Aneuploidy
Ansell Bywaters Elderking Syndrome
Arakawa Syndrome 2
AREDYLD Syndrome
Arima Syndrome
Arrhenoblastoma--Thyroid Adenoma
Arthritis
Asthma
Athrombia, Essential
Atrophy
Aughton Syndrome
Ayazi Syndrome
BADS Syndrome
Baetz-Greenwalt Syndrome
Bagatelle Cassidy Syndrome
Bangstad Syndrome
Bankart Lesions
Banki Syndrome
Banti's Syndrome
Basal Cell Carcinoma, Multiple
Basaran Yilmaz Syndrome
Bassoe Syndrome
Bazopoulou Kyrkanidou Syndrome
Beardwell Syndrome
Beemer Ertbruggen Syndrome
Bellini Chiumello Rimoldi Syndrome
Biemond Syndrome II
Bipolar And Related Disorders
Bipolar Disorder
Blepharo-cheilo-dontic Syndrome
Blount Disease
Boerhaave Syndrome
Bone Anteversion
Bone Retroversion
Bonneau Syndrome
Boudhina Yedes Khiari Syndrome
Brachioskeletogenital Syndrome
Brachycephalofrontonasal Dysplasia
Brachymesomelia Renal Syndrome
Brachymesophalangy 2 And 5
Bronchiolitis
Brunoni Syndrome
CAHMR Syndrome
Calabro Syndrome
CAMFAK Syndrome
Campomelia Cumming Type
Cancer
CANOMAD Syndrome
Cantalamessa Baldini Ambrosi Syndrome
Carcinogenesis
Carcinoma
Cardiocranial Syndrome
Carrington Syndrome
CATSHL Syndrome
Cerebelloparenchymal Disorder II
Cerebral Sarcoma
Cerebrooculonasal Syndrome
Chilaiditi Syndrome
Chondrosarcoma
Chordoma
CLAPO Syndrome
Cleidorhizomelic Syndrome
Colonic Neoplasms
Contrecoup Injury
Corneodermatoosseous Syndrome
Coxoauricular Syndrome
Cranioacrofacial Syndrome
Craniofaciofrontodigital Syndrome
Craniomicromelic Syndrome
Craniotelencephalic Dysplasia
Crome Syndrome
Curatolo Cilio Pessagno Syndrome
D-glycericacidemia
Daentl Towsend Siegel Syndrome
Daish Hardman Lamont Syndrome
Daneman Davy Mancer Syndrome
Davenport Donlan Syndrome
Death
Dermatoosteolysis Kirghizian Type
Devriendt Syndrome
Dieterich's Disease
Digitorenocerebral Syndrome
Dimauro Disease
Disease
Disease Progression
Diseases
Drachtman Weinblatt Sitarz Syndrome
Dysplasia Epiphysealis Hemimelica
Endometriosis
Faciocardiomelic Dysplasia, Lethal
Faciocardiomelic Syndrome
Faciocardiorenal Syndrome
Factor 8 Deficiency, Acquired
Fairbank Disease
Fetal Trimethadione Syndrome
Fibrosarcoma
Fibrosis
FLOTCH Syndrome
Flynn Aird Syndrome
Fountain Syndrome
Franceschini Vardeu Guala Syndrome
Freiberg's Disease
Frontoocular Syndrome
Furlong Syndrome
Furukawa Takagi Nakao Syndrome
Gas Bloat Syndrome
Gastric Sneezing
Gastrocutaneous Syndrome
Gemignani Syndrome
GEMSS Syndrome
Genoa Syndrome
Giacheti Syndrome
Glaucoma
Glioblastoma
GLUT1 DEFICIENCY SYNDROME 2
Gollop Coates Syndrome
GOMBO Syndrome
Granddad Syndrome
Grover's Disease
Grubben De Cock Borghgraef Syndrome
Gurrieri Sammito Bellussi Syndrome
Hadziselimovic Syndrome
Hagemoser Weinstein Bresnick Syndrome
Halal Syndrome
Hamanishi Ueba Tsuji Syndrome
Hamano Tsukamoto Syndrome
Hapnes Boman Skeie Syndrome
Hardikar Syndrome
Head And Neck Neoplasms
Herrmann Syndrome
Hersh Podruch Weisskopk Syndrome
Hooft Disease
Hordnes Engebretsen Knudtson Syndrome
Human Balantidiasis
Hunt's Syndrome
Hyperoxia
Hypoxia
Iida Kannari Syndrome
Immune System Diseases
Infection
Insulin-Like Growth Factor I, Resistance To
Ischemia
Jagell Holmgren Hofer Syndrome
Kaplowitz Bodurtha Syndrome
Karoshi Death
Kasabach-Merritt Syndrome
Kashani Strom Utley Syndrome
Katsantoni Papadakou Lagoyanni Syndrome
Kennerknecht Sorgo Oberhoffer Syndrome
Keratoacanthoma
Kleeblattschaedel Syndrome
Koone Rizzo Elias Syndrome
Kosztolanyi Syndrome
Krasnow Qazi Syndrome
Kuskokwim Disease
Kuzniecky Syndrome
Kyphomelic Dysplasia
Kyrle Disease
Lachiewicz Sibley Syndrome
Lacrimoauriculodentodigital Syndrome
Lambotte Syndrome
Lelis Syndrome
Lemierre Syndrome
Leukemia
Lymphoma
Lymphopenia
Lyngstadaas Syndrome
Malignant Mesenchymal Tumor
Malignant Teratocarcinosarcoma
Malouf Syndrome
Manouvrier Syndrome
Marchiafava-Bignami Disease
Marsden Syndrome
Massa Casaer Ceulemans Syndrome
Mastocytosis
May-Thurner Syndrome
Mehes Syndrome
Melanoma
Melanoma, Cutaneous Malignant
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 1
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 10
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 2
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 3
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 4
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 5
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 6
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 8
MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 9
Melhem Fahl Syndrome
Mengel Konigsmark Syndrome
Merlob Grunebaum Reisner Syndrome
Meyenburg-Altherr-Uehlinger Syndrome
Mirizzi Syndrome
Mollica Pavone Antener Syndrome
MOMES Syndrome
Mononen Karnes Senac Syndrome
Morgellons Disease
Multiple Chronic Conditions
Multiple Myeloma
Multiple Sclerosis
Muscular Atrophy
Nasodigitoacoustic Syndrome
Nasopharyngeal Carcinoma
Nathalie Syndrome
Necrosis
Neoplasms
Neoplasms, Plasma Cell
Neuroblastoma
Neurodegenerative Diseases
Neurofaciodigitorenal Syndrome
Nevo Syndrome
Nicolau Syndrome
Nievergelt Syndrome
Nivelon Nivelon Mabille Syndrome
Non-lissencephalic Cortical Dysplasia
Oculoauriculofrontonasal Syndrome
Oculocerebrocutaneous Syndrome
Oculodental Syndrome Rutherfurd Syndrome
Oculootofacial Dysplasia
Oculootoradial Syndrome
Oculopalatocerebral Syndrome
Oculopalatoskeletal Syndrome
Oculorenocerebellar Syndrome
Odontomicronychial Dysplasia
Onat Syndrome
Ophthalmomandibulomelic Dysplasia
Oroticaciduria 1
Oslam Syndrome
Osteoarthritis
Osteosarcoma
Otoonychoperoneal Syndrome
Pancreatic Cancer, Adult
Paraphilic Disorders
Pascual Castroviejo Syndrome
Pashayan Syndrome
Passovoy Factor
Pavone Fiumara Rizzo Syndrome
Pechet Factor Deficiency
Pelvic Organ Prolapse
Pelviscapular Dysplasia
PHACE Association
Pilotto Syndrome
Piussan Lenaerts Mathieu Syndrome
Plasminogen Deficiency, Type I
Podder-Tolmie Syndrome
Polycythemia
Polycythemia Vera
Postthrombotic Syndrome
Preeyasombat Varavithya Syndrome
Primary Dysautonomias
Primary Malignant Melanoma Of The Cervix
Primary Release Disorder Of Platelets
Prolapse
Propping Zerres Syndrome
Pseudoaminopterin Syndrome
Pseudoarylsulfatase A Deficiency
Pseudodiastrophic Dysplasia
Pseudotrisomy 13 Syndrome
Qazi Markouizos Syndrome
Radio Renal Syndrome
Rambaud Galian Syndrome
Ramer Ladda Syndrome
Reactive Angioendotheliomatosis
Recurrence
Reginato Schiapachasse Syndrome
Renal Aminoacidurias
Retinohepatoendocrinologic Syndrome
Rhabdomyosarcoma
RHYNS Syndrome
Ribbing Disease
Richards-Rundle Syndrome
Rombo Syndrome
Rosselli-Gulienetti Syndrome
Rudiger Syndrome
Sakoda Complex
Salcedo Syndrome
Sammartino De Crecchio Syndrome
Sandifer Syndrome
Sarcoma
Sarcoma, Myeloid
Satoyoshi Syndrome
Schlegelberger Grote Syndrome
Schofer Beetz Bohl Syndrome
Scholte Syndrome
Schrander-Stumpel Theunissen Hulsmans Syndrome
Sclerosis
Seaver Cassidy Syndrome
Seemanova Lesny Syndrome
Sener Syndrome
Severe Acute Respiratory Syndrome
Shapiro Syndrome
Silengo Lerone Pelizza Syndrome
Sillence Syndrome
Small Cell Lung Carcinoma
Sohval Soffer Syndrome
Spinal Muscular Atrophy 4
Spinal Muscular Atrophy, Ryukyuan Type
Starvation
Steinfeld Syndrome
Summitt Syndrome
SUNCT Syndrome
Susac Syndrome
Syndrome
Syringomas, Multiple
Tabatznik Syndrome
Tatsumi Factor Deficiency
Thoracolaryngopelvic Dysplasia
Thoracomelic Dysplasia
Three M Syndrome 2
Thyrocerebral-retinal Syndrome
Tonoki Syndrome
Translocation, Genetic
Trichodental Syndrome
Trichoodontoonychial Dysplasia
Trigger Finger Disorder
Trueb Burg Bottani Syndrome
Tsukahara Syndrome
Tucker Syndrome
Upington Disease
Vacuolar Neuromyopathy
Vascular Remodeling
VDAC Deficiency
Velofacioskeletal Syndrome
Verloove-Vanhorick Brubakk Syndrome
Volcke Soekarman Syndrome
Walbaum Titran Durieux Crepin Syndrome
Waldmann Disease
Warburton Anyane Yeboa Syndrome
Warman Mulliken Hayward Syndrome
Waterborne Diseases
Weismann Netter Syndrome
Wyburn Mason's Syndrome
Yusho Disease
Zazam Sheriff Phillips Syndrome
Zechi-Ceide Syndrome
ZINC, ELEVATED PLASMA
Zlotogora-Ogur Syndrome
Zuska's Disease

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: BCL2L1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BCL2L1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping