BCAR4 FISH Probe
The BCAR4 FISH probe is designed to hybridize to the BCAR4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCAR4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| BCAR4-20-RE | 20 (40 μL) | 200 μL |  |
|
| BCAR4-20-GO | 20 (40 μL) | 200 μL |  |
|
| BCAR4-20-GR | 20 (40 μL) | 200 μL |  |
|
| BCAR4-20-AQ | 20 (40 μL) | 200 μL |  |
|
| BCAR4-20-DIG | 20 (40 μL) | 200 μL |  |
|
| BCAR4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene produces a spliced long non-coding RNA (lncRNA) that has been implicated in breast cancer metastasis. It was originally identified in a screen for genes responsible for the development of resistance to anti-estrogens in breast cancer cells. It is thought that release of CCL21 enables this lncRNA to bind to the SNIP1 and PNUTS transcription factors, thereby activating a non-canonical GLI-dependent hedgehog signaling pathway that promotes cancer cell migration and invasion. A similar gene in cow expresses a protein in mature oocytes and preimplantation embryos. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: BCAR4
Gene Name: Breast Cancer Anti-estrogen Resistance 4 (non-protein Coding)
Chromosome: CHR16: 11913691-11922689
Locus: 16p13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: BCAR4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCAR4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping