BCAR3 FISH Probe
The BCAR3 FISH probe is designed to hybridize to the BCAR3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCAR3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BCAR3-20-RE | 20 (40 μL) | 200 μL |  |
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| BCAR3-20-GO | 20 (40 μL) | 200 μL |  |
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| BCAR3-20-GR | 20 (40 μL) | 200 μL |  |
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| BCAR3-20-AQ | 20 (40 μL) | 200 μL |  |
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| BCAR3-20-DIG | 20 (40 μL) | 200 μL |  |
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| BCAR3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: BCAR3
Gene Name: BCAR3, NSP Family Adaptor Protein
Chromosome: CHR1: 94027348-94147385
Locus: 1p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BCAR3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCAR3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping