BCAR1 Break Apart FISH Probe
Empire Genomics’ BCAR1 Break Apart FISH Probe is designed to flank the BCAR1 gene and is typically used for detecting BCAR1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCAR1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| BCAR1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
Gene Details
Gene Symbol: BCAR1
Gene Name: BCAR1, Cas Family Scaffolding Protein
Chromosome: CHR16: 75262927-75301951
Locus: 16q23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: BCAR1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCAR1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping