BBS6 FISH Probe
The BBS6 FISH probe is designed to hybridize to the BBS6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MKKS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MKKS-20-RE | 20 (40 μL) | 200 μL |  |
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| MKKS-20-GO | 20 (40 μL) | 200 μL |  |
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| MKKS-20-GR | 20 (40 μL) | 200 μL |  |
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| MKKS-20-AQ | 20 (40 μL) | 200 μL |  |
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| MKKS-20-DIG | 20 (40 μL) | 200 μL |  |
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| MKKS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins. Mutations in this gene have been observed in patients with Bardet-Biedl syndrome type 6, also known as McKusick-Kaufman syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Details
Gene Symbol: MKKS
Gene Name: McKusick-Kaufman Syndrome
Chromosome: CHR20: 10385832-10414866
Locus: 20p12.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BBS6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MKKS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping