BBS4 Break Apart FISH Probe
Empire Genomics’ BBS4 Break Apart FISH Probe is designed to flank the BBS4 gene and is typically used for detecting BBS4 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BBS4BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| BBS4BA-20-AQOR | 20 (40 μL) | 200 μL |
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| BBS4BA-20-GOGR | 20 (40 μL) | 200 μL |
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| BBS4BA-20-GORE | 20 (40 μL) | 200 μL |
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| BBS4BA-20-GRGO | 20 (40 μL) | 200 μL |
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| BBS4BA-20-GROR | 20 (40 μL) | 200 μL |
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| BBS4BA-20-GRRE | 20 (40 μL) | 200 μL |
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| BBS4BA-20-REGO | 20 (40 μL) | 200 μL |
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| BBS4BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with seven other BBS proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: BBS4
Gene Name: Bardet-Biedl Syndrome 4
Chromosome: CHR15: 72978525-73030817
Locus: 15q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BBS4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BBS4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping