BBS2- FISH Probe
The BBS2- FISH probe is designed to hybridize to the BBS2- gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BBS7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BBS7-20-RE | 20 (40 μL) | 200 μL |  |
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| BBS7-20-GO | 20 (40 μL) | 200 μL |  |
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| BBS7-20-GR | 20 (40 μL) | 200 μL |  |
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| BBS7-20-AQ | 20 (40 μL) | 200 μL |  |
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| BBS7-20-DIG | 20 (40 μL) | 200 μL |  |
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| BBS7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy; however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: BBS7
Gene Name: Bardet-Biedl Syndrome 7
Chromosome: CHR4: 122745483-122791652
Locus: 4q27
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BBS2- FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BBS7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping