BB2R FISH Probe
The BB2R FISH probe is designed to hybridize to the BB2R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GRPR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GRPR-20-RE | 20 (40 μL) | 200 μL |  |
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| GRPR-20-GO | 20 (40 μL) | 200 μL |  |
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| GRPR-20-GR | 20 (40 μL) | 200 μL |  |
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| GRPR-20-AQ | 20 (40 μL) | 200 μL |  |
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| GRPR-20-DIG | 20 (40 μL) | 200 μL |  |
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| GRPR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GRPR
Gene Name: Gastrin Releasing Peptide Receptor
Chromosome: CHRX: 16141423-16171641
Locus: Xp22.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BB2R FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRPR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping