BAX-ALPHA FISH Probe
The BAX-ALPHA FISH probe is designed to hybridize to the BAX-ALPHA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BAX-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| BAX-20-RE | 20 (40 μL) | 200 μL |  |
|
| BAX-20-GO | 20 (40 μL) | 200 μL |  |
|
| BAX-20-GR | 20 (40 μL) | 200 μL |  |
|
| BAX-20-AQ | 20 (40 μL) | 200 μL |  |
|
| BAX-20-DIG | 20 (40 μL) | 200 μL |  |
|
| BAX-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: BAX
Gene Name: BCL2 Associated X, Apoptosis Regulator
Chromosome: CHR19: 49458116-49465055
Locus: 19q13.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: BAX-ALPHA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BAX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping