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BARD1 Break Apart FISH Probe

Empire Genomics’ BARD1 Break Apart FISH Probe is designed to flank the BARD1 gene and is typically used for detecting BARD1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BARD1BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
BARD1BA-20-AQOR 20 (40 μL) 200 μL
BARD1BA-20-GOGR 20 (40 μL) 200 μL
BARD1BA-20-GORE 20 (40 μL) 200 μL
BARD1BA-20-GRGO 20 (40 μL) 200 μL
BARD1BA-20-GRRE 20 (40 μL) 200 μL
BARD1BA-20-ORGR 20 (40 μL) 200 μL
BARD1BA-20-REGO 20 (40 μL) 200 μL
BARD1BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Gene Details

Gene Symbol: BARD1

Gene Name: BRCA1 Associated RING Domain 1

Chromosome: CHR2: 215593274-215674428

Locus: 2q35

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: BARD1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BARD1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping