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BARD1 FISH Probe

The BARD1 FISH probe is designed to hybridize to the BARD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
BARD1-20-OR  (Standard Design) 20 (40 μL) 200 μL
BARD1-20-RE 20 (40 μL) 200 μL
BARD1-20-GO 20 (40 μL) 200 μL
BARD1-20-GR 20 (40 μL) 200 μL
BARD1-20-AQ 20 (40 μL) 200 μL
BARD1-20-DIG 20 (40 μL) 200 μL
BARD1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Gene Details

Gene Symbol: BARD1

Gene Name: BRCA1 Associated RING Domain 1

Chromosome: CHR2: 215593274-215674428

Locus: 2q35

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: BARD1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BARD1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping