BAG-3 FISH Probe
The BAG-3 FISH probe is designed to hybridize to the BAG-3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BAG3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BAG3-20-RE | 20 (40 μL) | 200 μL |  |
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| BAG3-20-GO | 20 (40 μL) | 200 μL |  |
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| BAG3-20-GR | 20 (40 μL) | 200 μL |  |
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| BAG3-20-AQ | 20 (40 μL) | 200 μL |  |
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| BAG3-20-DIG | 20 (40 μL) | 200 μL |  |
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| BAG3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: BAG3
Gene Name: BCL2 Associated Athanogene 3
Chromosome: CHR10: 121410881-121437329
Locus: 10q26.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BAG-3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BAG3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping