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BAD FISH Probe

The BAD FISH probe is designed to hybridize to the BAD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
BAD-20-OR  (Standard Design) 20 (40 μL) 200 μL
BAD-20-RE 20 (40 μL) 200 μL
BAD-20-GO 20 (40 μL) 200 μL
BAD-20-GR 20 (40 μL) 200 μL
BAD-20-AQ 20 (40 μL) 200 μL
BAD-20-DIG 20 (40 μL) 200 μL
BAD-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: BAD

Gene Name: BCL2 Associated Agonist Of Cell Death

Chromosome: CHR11: 64037299-64052176

Locus: 11q13.1

Gene Diseases

The BAD gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
Abrikosov's Tumor
Acquired Hypoprothrombinemia
Acrocephalopolysyndactyly Type II
Adenocarcinoid Tumor
Androblastoma Of Ovary
Arthritis
Blount Disease
Bone Anteversion
Bone Retroversion
Brachymesophalangy 2 And 5
Campomelia Cumming Type
Cancer
Carcinoma
Cerebral Sarcoma
Colonic Neoplasms
Death
Dermatoosteolysis Kirghizian Type
Dieterich's Disease
Dimauro Disease
Disease
Fairbank Disease
Freiberg's Disease
Gastric Sneezing
Glioma
Grover's Disease
Hooft Disease
Human Balantidiasis
Hypoxia
Infection
Influenza, Human
Intestinal Helminthiasis
Karoshi Death
Kuskokwim Disease
Kyrle Disease
Leukemia
Lymphoma
Lymphoma, Large B-Cell, Diffuse
Malignant Teratocarcinosarcoma
Marchiafava-Bignami Disease
Maturity-Onset Diabetes Of The Young, Type 1
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 10
MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 11
Maturity-Onset Diabetes Of The Young, Type 2
Maturity-Onset Diabetes Of The Young, Type 3
Maturity-Onset Diabetes Of The Young, Type 4
Maturity-Onset Diabetes Of The Young, Type 7
Maturity-Onset Diabetes Of The Young, Type 9
Melanoma
Microtrauma, Physical
Morgellons Disease
Nasopharyngeal Carcinoma
Neoplasms
Neuroblastoma
Oroticaciduria 1
Passovoy Factor
Pelvic Organ Prolapse
PHACE Association
Pigmented Nodular Adrenocortical Disease, Primary, 1
Pigmented Nodular Adrenocortical Disease, Primary, 2
Primary Dysautonomias
Prolapse
Reactive Angioendotheliomatosis
Renal Aminoacidurias
Ribbing Disease
Sakoda Complex
Sarcoidosis
Sarcoma
Small Cell Lung Carcinoma
Translocation, Genetic
Upington Disease
Waldmann Disease
Yusho Disease
Zuska's Disease

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: BAD FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: BAD-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping