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BA3A1C FISH Probe

The BA3A1C FISH probe is designed to hybridize to the BA3A1C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CRYBA1-20-OR  (Standard Design) 20 (40 μL) 200 μL
CRYBA1-20-RE 20 (40 μL) 200 μL
CRYBA1-20-GO 20 (40 μL) 200 μL
CRYBA1-20-GR 20 (40 μL) 200 μL
CRYBA1-20-AQ 20 (40 μL) 200 μL
CRYBA1-20-DIG 20 (40 μL) 200 μL
CRYBA1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CRYBA1

Gene Name: Crystallin Beta A1

Chromosome: CHR17: 27573874-27581502

Locus: 17q11.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: BA3A1C FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CRYBA1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping