B5R FISH Probe
The B5R FISH probe is designed to hybridize to the B5R gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYB5R3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYB5R3-20-RE | 20 (40 μL) | 200 μL |  |
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| CYB5R3-20-GO | 20 (40 μL) | 200 μL |  |
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| CYB5R3-20-GR | 20 (40 μL) | 200 μL |  |
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| CYB5R3-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYB5R3-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYB5R3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq, Jan 2010]
Gene Details
Gene Symbol: CYB5R3
Gene Name: Cytochrome B5 Reductase 3
Chromosome: CHR22: 43013845-43045405
Locus: 22q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: B5R FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYB5R3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping