B23 FISH Probe
The B23 FISH probe is designed to hybridize to the B23 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NPM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NPM1-20-RE | 20 (40 μL) | 200 μL |  |
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| NPM1-20-GO | 20 (40 μL) | 200 μL |  |
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| NPM1-20-GR | 20 (40 μL) | 200 μL |  |
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| NPM1-20-AQ | 20 (40 μL) | 200 μL |  |
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| NPM1-20-DIG | 20 (40 μL) | 200 μL |  |
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| NPM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: NPM1
Gene Name: Nucleophosmin 1
Chromosome: CHR5: 170814707-170837888
Locus: 5q35.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: B23 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NPM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping