AV138748 FISH Probe
The AV138748 FISH probe is designed to hybridize to the AV138748 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BCDIN3D-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BCDIN3D-20-RE | 20 (40 μL) | 200 μL |  |
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| BCDIN3D-20-GO | 20 (40 μL) | 200 μL |  |
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| BCDIN3D-20-GR | 20 (40 μL) | 200 μL |  |
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| BCDIN3D-20-AQ | 20 (40 μL) | 200 μL |  |
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| BCDIN3D-20-DIG | 20 (40 μL) | 200 μL |  |
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| BCDIN3D-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]
Gene Details
Gene Symbol: BCDIN3D
Gene Name: BCDIN3 Domain Containing RNA Methyltransferase
Chromosome: CHR12: 50229825-50236912
Locus: 12q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AV138748 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BCDIN3D-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping