AV095280 FISH Probe
The AV095280 FISH probe is designed to hybridize to the AV095280 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
NRAS-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
NRAS-20-RE | 20 (40 μL) | 200 μL | ||
NRAS-20-GO | 20 (40 μL) | 200 μL | ||
NRAS-20-GR | 20 (40 μL) | 200 μL | ||
NRAS-20-AQ | 20 (40 μL) | 200 μL | ||
NRAS-20-DIG | 20 (40 μL) | 200 μL | ||
NRAS-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]
Gene Details
Gene Symbol: NRAS
Gene Name: NRAS Proto-oncogene, GTPase
Chromosome: CHR1: 115247084-115259515
Locus: 1p13.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: AV095280 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NRAS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping