AV021745 FISH Probe
The AV021745 FISH probe is designed to hybridize to the AV021745 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PILRA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PILRA-20-RE | 20 (40 μL) | 200 μL |  |
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| PILRA-20-GO | 20 (40 μL) | 200 μL |  |
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| PILRA-20-GR | 20 (40 μL) | 200 μL |  |
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| PILRA-20-AQ | 20 (40 μL) | 200 μL |  |
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| PILRA-20-DIG | 20 (40 μL) | 200 μL |  |
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| PILRA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the ITIM-bearing member of the receptor pair, which functions in the inhibitory role. Alternative splicing has been observed at this locus and three variants, each encoding a distinct isoform, are described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PILRA
Gene Name: Paired Immunoglobin Like Type 2 Receptor Alpha
Chromosome: CHR7: 99971067-99997722
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AV021745 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PILRA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping