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AURKA FISH Probe

The AURKA FISH probe is designed to hybridize to the AURKA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

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Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
AURKA-20-OR  (Standard Design) 20 (40 μL) 200 μL
AURKA-20-RE 20 (40 μL) 200 μL
AURKA-20-GO 20 (40 μL) 200 μL
AURKA-20-GR 20 (40 μL) 200 μL
AURKA-20-AQ 20 (40 μL) 200 μL
AURKA-20-DIG 20 (40 μL) 200 μL
AURKA-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: AURKA

Gene Name: Aurora Kinase A

Chromosome: CHR20: 54944444-54967351

Locus: 20q13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Acral melanomas vary considerably in their molecular, histological, and clinical presentation. In this study, acral melanomas from dorsal, volar, and subungual-interdigital body sites were assessed using several tests, including FISH. Our TERT, CCND1, CDK4, AURKA, CDKN2A, PAK1, PTEN, NF1, and GAB2 probes were used to detect copy number variations in these genes. Genetic profiles were found to be tightly tied to UV exposure.
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Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Acral melanomas vary considerably in their molecular, histological, and clinical presentation. In this study, acral melanomas from dorsal, volar, and subungual-interdigital body sites were assessed using several tests, including FISH. Our TERT, CCND1, CDK4, AURKA, CDKN2A, PAK1, PTEN, NF1, and GAB2 probes were used to detect copy number variations in these genes. Genetic profiles were found to be tightly tied to UV exposure.
Read More

Product Details

Product: AURKA FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: AURKA-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping