AUP1 Break Apart FISH Probe
Empire Genomics’ AUP1 Break Apart FISH Probe is designed to flank the AUP1 gene and is typically used for detecting AUP1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AUP1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| AUP1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| AUP1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| AUP1BA-20-GORE | 20 (40 μL) | 200 μL |
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| AUP1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| AUP1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| AUP1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| AUP1BA-20-REGO | 20 (40 μL) | 200 μL |
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| AUP1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: AUP1
Gene Name: AUP1, Lipid Droplet Regulating VLDL Assembly Factor
Chromosome: CHR2: 74753774-74756974
Locus: 2p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AUP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AUP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping