AUP1 FISH Probe
The AUP1 FISH probe is designed to hybridize to the AUP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AUP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AUP1-20-RE | 20 (40 μL) | 200 μL |  |
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| AUP1-20-GO | 20 (40 μL) | 200 μL |  |
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| AUP1-20-GR | 20 (40 μL) | 200 μL |  |
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| AUP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| AUP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| AUP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: AUP1
Gene Name: AUP1, Lipid Droplet Regulating VLDL Assembly Factor
Chromosome: CHR2: 74753774-74756974
Locus: 2p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AUP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AUP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping