AUH FISH Probe
The AUH FISH probe is designed to hybridize to the AUH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AUH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AUH-20-RE | 20 (40 μL) | 200 μL |  |
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| AUH-20-GO | 20 (40 μL) | 200 μL |  |
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| AUH-20-GR | 20 (40 μL) | 200 μL |  |
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| AUH-20-AQ | 20 (40 μL) | 200 μL |  |
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| AUH-20-DIG | 20 (40 μL) | 200 μL |  |
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| AUH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Gene Details
Gene Symbol: AUH
Gene Name: AU RNA Binding Methylglutaconyl-CoA Hydratase
Chromosome: CHR9: 93976096-94124206
Locus: 9q22.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AUH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AUH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping