ATXN8 Break Apart FISH Probe
Empire Genomics’ ATXN8 Break Apart FISH Probe is designed to flank the ATXN8 gene and is typically used for detecting ATXN8 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATXN8BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-AQOR | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-GORE | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-REGO | 20 (40 μL) | 200 μL |
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| ATXN8BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Aug 2009]
Gene Details
Gene Symbol: TWNK
Gene Name: Twinkle MtDNA Helicase
Chromosome: CHR10: 100987526-100994402
Locus: 10q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATXN8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TWNK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping