ATRX Break Apart FISH Probe
Empire Genomics’ ATRX Break Apart FISH Probe is designed to flank the ATRX gene and is typically used for detecting ATRX rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATRXBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATRXBA-20-AQOR | 20 (40 μL) | 200 μL |
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| ATRXBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ATRXBA-20-GORE | 20 (40 μL) | 200 μL |
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| ATRXBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ATRXBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ATRXBA-20-ORGR | 20 (40 μL) | 200 μL |
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| ATRXBA-20-REGO | 20 (40 μL) | 200 μL |
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| ATRXBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017]
Gene Details
Gene Symbol: ATRX
Gene Name: ATRX, Chromatin Remodeler
Chromosome: CHRX: 76760355-77041719
Locus: Xq21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATRX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ATRX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping