ATP8A2 Break Apart FISH Probe
Empire Genomics’ ATP8A2 Break Apart FISH Probe is designed to flank the ATP8A2 gene and is typically used for detecting ATP8A2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATP8A2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-GORE | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-GROR | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-REGO | 20 (40 μL) | 200 μL |
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| ATP8A2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a member of the P4 ATPase family of proteins, which are thought to be involved in a process called lipid flipping, whereby phospholipids are translocated inwards from the exoplasmic leaflet to the cytosolic leaflet of the cell membrane, which aids in generating and maintaining asymmetry in membrane lipids. This protein is predicted to contain an E1 E2 ATPase, a haloacid dehalogenase-like hydrolase (HAD) domain, and multiple transmembrane domains. Associations between this protein and cell cycle control protein 50A are important for translocation of phosphatidylserine across membranes. Mutations in this gene have been associated with a syndrome (CAMRQ4) characterized by cerebellar ataxia and cognitive disabilities. In addition, a translocation breakpoint within this gene was observed in an individual with neurological dysfunction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
Gene Details
Gene Symbol: ATP8A2
Gene Name: ATPase Phospholipid Transporting 8A2
Chromosome: CHR13: 25946208-26595420
Locus: 13q12.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATP8A2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ATP8A2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping