SEARCH OUR PRODUCT CATALOG

ATIC FISH Probe

The ATIC FISH probe is designed to hybridize to the ATIC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ATIC-20-OR  (Standard Design) 20 (40 μL) 200 μL
ATIC-20-RE 20 (40 μL) 200 μL
ATIC-20-GO 20 (40 μL) 200 μL
ATIC-20-GR 20 (40 μL) 200 μL
ATIC-20-AQ 20 (40 μL) 200 μL
ATIC-20-DIG 20 (40 μL) 200 μL
ATIC-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]

Gene Details

Gene Symbol: ATIC

Gene Name: 5-aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase

Chromosome: CHR2: 216176678-216214496

Locus: 2q35

Gene Diseases

The ATIC gene has been associated with the following diseases:

Disease Name
2-Hydroxyglutaricaciduria
Adenocarcinoma
Androblastoma Of Ovary
Arthritis
Arthritis, Juvenile
Blindness
Blount Disease
Bone Anteversion
Bone Retroversion
Brachymesophalangy 2 And 5
D-glycericacidemia
Dieterich's Disease
Dimauro Disease
Disease
Fairbank Disease
Freiberg's Disease
Grover's Disease
Hooft Disease
Human Balantidiasis
Kuskokwim Disease
Kyrle Disease
Marchiafava-Bignami Disease
Morgellons Disease
Oroticaciduria 1
Osteosarcoma
PHACE Association
Primary Dysautonomias
Pseudoarylsulfatase A Deficiency
Ribbing Disease
Sakoda Complex
Sulfhemoglobinemia, Congenital
Translocation, Genetic
Upington Disease
Waldmann Disease
Yusho Disease
Zuska's Disease

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ATIC FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ATIC-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping