ATF6B Break Apart FISH Probe
Empire Genomics’ ATF6B Break Apart FISH Probe is designed to flank the ATF6B gene and is typically used for detecting ATF6B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATF6BBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-AQOR | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-GORE | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-ORGR | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-REGO | 20 (40 μL) | 200 μL |
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| ATF6BBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: ATF6B
Gene Name: Activating Transcription Factor 6 Beta
Chromosome: CHR6: 32083044-32096017
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATF6B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ATF6B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping