ATF6B FISH Probe
The ATF6B FISH probe is designed to hybridize to the ATF6B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ATF6B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ATF6B-20-RE | 20 (40 μL) | 200 μL |  |
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| ATF6B-20-GO | 20 (40 μL) | 200 μL |  |
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| ATF6B-20-GR | 20 (40 μL) | 200 μL |  |
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| ATF6B-20-AQ | 20 (40 μL) | 200 μL |  |
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| ATF6B-20-DIG | 20 (40 μL) | 200 μL |  |
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| ATF6B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: ATF6B
Gene Name: Activating Transcription Factor 6 Beta
Chromosome: CHR6: 32083044-32096017
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATF6B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ATF6B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping