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ATF6 FISH Probe

The ATF6 FISH probe is designed to hybridize to the ATF6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ATF6-20-OR  (Standard Design) 20 (40 μL) 200 μL
ATF6-20-RE 20 (40 μL) 200 μL
ATF6-20-GO 20 (40 μL) 200 μL
ATF6-20-GR 20 (40 μL) 200 μL
ATF6-20-AQ 20 (40 μL) 200 μL
ATF6-20-DIG 20 (40 μL) 200 μL
ATF6-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011]

Gene Details

Gene Symbol: ATF6

Gene Name: Activating Transcription Factor 6

Chromosome: CHR1: 161736033-161933860

Locus: 1q23.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ATF6 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ATF6-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping