ATF2 Break Apart FISH Probe
Empire Genomics’ ATF2 Break Apart FISH Probe is designed to flank the ATF2 gene and is typically used for detecting ATF2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ATF2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| ATF2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| ATF2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ATF2BA-20-GORE | 20 (40 μL) | 200 μL |
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| ATF2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ATF2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ATF2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ATF2BA-20-REGO | 20 (40 μL) | 200 μL |
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| ATF2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: ATF2
Gene Name: Activating Transcription Factor 2
Chromosome: CHR2: 175939005-176032897
Locus: 2q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ATF2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ATF2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping