ASXL1 FISH Probe
The ASXL1 FISH probe is designed to hybridize to the ASXL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASXL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ASXL1-20-RE | 20 (40 μL) | 200 μL |  |
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| ASXL1-20-GO | 20 (40 μL) | 200 μL |  |
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| ASXL1-20-GR | 20 (40 μL) | 200 μL |  |
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| ASXL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ASXL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ASXL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: ASXL1
Gene Name: Additional Sex Combs Like 1, Transcriptional Regulator
Chromosome: CHR20: 30946146-31027122
Locus: 20q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ASXL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ASXL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping