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ASXL1 FISH Probe

The ASXL1 FISH probe is designed to hybridize to the ASXL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
ASXL1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ASXL1-20-RE 20 (40 μL) 200 μL
ASXL1-20-GO 20 (40 μL) 200 μL
ASXL1-20-GR 20 (40 μL) 200 μL
ASXL1-20-AQ 20 (40 μL) 200 μL
ASXL1-20-DIG 20 (40 μL) 200 μL
ASXL1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Gene Details

Gene Symbol: ASXL1

Gene Name: Additional Sex Combs Like 1, Transcriptional Regulator

Chromosome: CHR20: 30946146-31027122

Locus: 20q11.21

Gene Diseases

Our database currently has no diseases associated with the ASXL1 gene.

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: ASXL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ASXL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping