ASPH FISH Probe
The ASPH FISH probe is designed to hybridize to the ASPH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ASPH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ASPH-20-RE | 20 (40 μL) | 200 μL |  |
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| ASPH-20-GO | 20 (40 μL) | 200 μL |  |
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| ASPH-20-GR | 20 (40 μL) | 200 μL |  |
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| ASPH-20-AQ | 20 (40 μL) | 200 μL |  |
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| ASPH-20-DIG | 20 (40 μL) | 200 μL |  |
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| ASPH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: ASPH
Gene Name: Aspartate Beta-hydroxylase
Chromosome: CHR8: 62413114-62627199
Locus: 8q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ASPH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ASPH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping