ARNTL FISH Probe
The ARNTL FISH probe is designed to hybridize to the ARNTL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ARNTL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ARNTL-20-RE | 20 (40 μL) | 200 μL |  |
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| ARNTL-20-GO | 20 (40 μL) | 200 μL |  |
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| ARNTL-20-GR | 20 (40 μL) | 200 μL |  |
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| ARNTL-20-AQ | 20 (40 μL) | 200 μL |  |
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| ARNTL-20-DIG | 20 (40 μL) | 200 μL |  |
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| ARNTL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: ARNTL
Gene Name: Aryl Hydrocarbon Receptor Nuclear Translocator Like
Chromosome: CHR11: 13299324-13408812
Locus: 11p15.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ARNTL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ARNTL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping