ARMD13 FISH Probe
The ARMD13 FISH probe is designed to hybridize to the ARMD13 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CFI-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CFI-20-RE | 20 (40 μL) | 200 μL |  |
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| CFI-20-GO | 20 (40 μL) | 200 μL |  |
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| CFI-20-GR | 20 (40 μL) | 200 μL |  |
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| CFI-20-AQ | 20 (40 μL) | 200 μL |  |
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| CFI-20-DIG | 20 (40 μL) | 200 μL |  |
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| CFI-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uremic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immune deposits and age-related macular degeneration are other conditions associated with mutations of this gene. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: CFI
Gene Name: Complement Factor I
Chromosome: CHR4: 110661847-110723335
Locus: 4q25
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ARMD13 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CFI-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping