ARID1B Break Apart FISH Probe
Empire Genomics’ ARID1B Break Apart FISH Probe is designed to flank the ARID1B gene and is typically used for detecting ARID1B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARID1BBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-AQOR | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-GORE | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-GROR | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-REGO | 20 (40 μL) | 200 μL |
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| ARID1BBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ARID1A
Gene Name: AT-rich Interaction Domain 1A
Chromosome: CHR1: 27022521-27108601
Locus: 1p36.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ARID1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ARID1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping