ARHGEF3 Break Apart FISH Probe
Empire Genomics’ ARHGEF3 Break Apart FISH Probe is designed to flank the ARHGEF3 gene and is typically used for detecting ARHGEF3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ARHGEF3BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-GORE | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-ORGR | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-REGO | 20 (40 μL) | 200 μL |
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| ARHGEF3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ARHGEF3
Gene Name: Rho Guanine Nucleotide Exchange Factor 3
Chromosome: CHR3: 56761445-57113336
Locus: 3p14.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ARHGEF3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ARHGEF3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping