ARF GAP GIT2 FISH Probe
The ARF GAP GIT2 FISH probe is designed to hybridize to the ARF GAP GIT2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GIT2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GIT2-20-RE | 20 (40 μL) | 200 μL |  |
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| GIT2-20-GO | 20 (40 μL) | 200 μL |  |
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| GIT2-20-GR | 20 (40 μL) | 200 μL |  |
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| GIT2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GIT2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GIT2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding. [provided by RefSeq, Sep 2008]
Gene Details
Gene Symbol: GIT2
Gene Name: GIT ArfGAP 2
Chromosome: CHR12: 110367606-110434194
Locus: 12q24.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ARF GAP GIT2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GIT2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping