APY FISH Probe
The APY FISH probe is designed to hybridize to the APY gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MS4A2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MS4A2-20-RE | 20 (40 μL) | 200 μL |  |
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| MS4A2-20-GO | 20 (40 μL) | 200 μL |  |
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| MS4A2-20-GR | 20 (40 μL) | 200 μL |  |
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| MS4A2-20-AQ | 20 (40 μL) | 200 μL |  |
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| MS4A2-20-DIG | 20 (40 μL) | 200 μL |  |
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| MS4A2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of membrane-spanning 4A gene family members. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described but require experimental validation. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: MS4A2
Gene Name: Membrane Spanning 4-domains A2
Chromosome: CHR11: 59856136-59865940
Locus: 11q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APY FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MS4A2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping