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APR FISH Probe

The APR FISH probe is designed to hybridize to the APR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
LRP1-20-OR  (Standard Design) 20 (40 μL) 200 μL
LRP1-20-RE 20 (40 μL) 200 μL
LRP1-20-GO 20 (40 μL) 200 μL
LRP1-20-GR 20 (40 μL) 200 μL
LRP1-20-AQ 20 (40 μL) 200 μL
LRP1-20-DIG 20 (40 μL) 200 μL
LRP1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]

Gene Details

Gene Symbol: LRP1

Gene Name: LDL Receptor Related Protein 1

Chromosome: CHR12: 57522281-57607125

Locus: 12q13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: APR FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: LRP1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping