APOE FISH Probe
The APOE FISH probe is designed to hybridize to the APOE gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
APOE-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
APOE-20-RE | 20 (40 μL) | 200 μL | ||
APOE-20-GO | 20 (40 μL) | 200 μL | ||
APOE-20-GR | 20 (40 μL) | 200 μL | ||
APOE-20-AQ | 20 (40 μL) | 200 μL | ||
APOE-20-DIG | 20 (40 μL) | 200 μL | ||
APOE-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]
Gene Details
Gene Symbol: APOE
Gene Name: Apolipoprotein E
Chromosome: CHR19: 45409038-45412650
Locus: 19q13.32
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: APOE FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APOE-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping