APOBEC3A Break Apart FISH Probe
Empire Genomics’ APOBEC3A Break Apart FISH Probe is designed to flank the APOBEC3A gene and is typically used for detecting APOBEC3A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| APOBEC3ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-GORE | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-GROR | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-REGO | 20 (40 μL) | 200 μL |
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| APOBEC3ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
Gene Details
Gene Symbol: APOBEC3A
Gene Name: Apolipoprotein B MRNA Editing Enzyme Catalytic Subunit 3A
Chromosome: CHR22: 39353526-39388783
Locus: 22q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APOBEC3A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APOBEC3A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping