APOB-ICR FISH Probe
The APOB-ICR FISH probe is designed to hybridize to the APOB-ICR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| APOB-ICR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| APOB-ICR-20-RE | 20 (40 μL) | 200 μL |  |
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| APOB-ICR-20-GO | 20 (40 μL) | 200 μL |  |
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| APOB-ICR-20-GR | 20 (40 μL) | 200 μL |  |
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| APOB-ICR-20-AQ | 20 (40 μL) | 200 μL |  |
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| APOB-ICR-20-DIG | 20 (40 μL) | 200 μL |  |
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| APOB-ICR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This region represents a portion of a larger DNase I sensitive domain in intestinal cells. It contains DNase I hypersensitive sites corresponding to intestinal enhancers and other regulators of the apolipoprotein B (APOB) gene, located greater than 50 kb downstream. Enhancer activity is associated with binding by C/EBP, forkhead, and nuclear receptor family proteins, and responds to signalling by transforming growth factor beta. An additional regulatory sequence binds transcriptional repressor CTCF and can act as an insulator and an enhancer blocker. This region also includes a putative scaffold/matrix attachment region (S/MAR). [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: APOB-ICR
Gene Name: APOB Intestinal Control Region (ICR)
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APOB-ICR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: APOB-ICR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping