APO3L FISH Probe
The APO3L FISH probe is designed to hybridize to the APO3L gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
TNFSF12-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
TNFSF12-20-RE | 20 (40 μL) | 200 μL | ||
TNFSF12-20-GO | 20 (40 μL) | 200 μL | ||
TNFSF12-20-GR | 20 (40 μL) | 200 μL | ||
TNFSF12-20-AQ | 20 (40 μL) | 200 μL | ||
TNFSF12-20-DIG | 20 (40 μL) | 200 μL | ||
TNFSF12-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
Gene Details
Gene Symbol: TNFSF12
Gene Name: TNF Superfamily Member 12
Chromosome: CHR17: 7452374-7461207
Locus: 17p13.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APO3L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TNFSF12-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping